I-2-chloro-5-chloromethyl pyridine
Ulwazi olusisiseko:
Igama leKhemikhali: 2-chloro-5-chloromethyl pyridine
Inombolo ye-CAS: 70258-18-3
Ifomula yemolekyuli: C6H5Cl2N
Ubunzima bemolekyuli: 162.02
Inombolo ye-EINECS: 615-091-8
Ifomula yolwakhiwo:
Iindidi eziyeleleneyo: Abaphakathi - abaphakathi kwezibulali zinambuzane; abaphakathi bamayeza; Iikhemikhali ze-Organic izinto ezikrwada kunye neziphakathi;
Indawo yokunyibilika: 37-42 °C(lit.) Indawo yokubila: 267.08°C (uqikelelo olurhabaxa) Ubuninzi: 1.4411 (uqikelelo olurhabaxa) Isalathiso seRefractive: 1.6000 (uqikelelo) Indawo yokudanyaza: >230 °F Ukunyibilika: Ukunyibilika kwi-DMSO (a encinci), i-methanol (incinci), enganyibiliki emanzini. Uphawu: beige crystal. I-Acidity coefficient (pKa)-0.75±0.10(Iqikelelweyo)
| iinkcukacha | iyunithi | umgangatho |
| Imbonakalo | Ayinambala ukuya kwikristale beige | |
| Umxholo ophambili | % | ≥98.0% |
| Ukufuma | % | ≤0.5 |
I-2-chloro-5-chloromethyl pyridine (i-CCMP) yinto ebalulekileyo ye-pharmaceutical intermediate kunye ne-intermediate ebalulekileyo ye-synthesis ye-pyridine pesticide agents ezifana ne-imidacloprid, i-acetamiprid, i-fluazinam, njl.
Kukho iindlela ezininzi zokuhlanganisa i-2-chloro-5-chloromethyl pyridine. Okwangoku, i-2-chloro-5-methylpyridine isetyenziswa njengento eluhlaza kwishishini, oko kukuthi, i-2-chloro-5-methylpyridine i-chlorine yi-2-chloro-5-methylpyridine phambi kwe-catalyst ukufumana i-2-chloro. -5-chloromethyl pyridine. I-2-chloro-5-methylpyridine kunye ne-solvent yongezwa kwi-kettle ye-chlorination, i-catalyst yongezwa, kwaye igesi ye-chlorine ifakwe kwi-reaction phantsi kwemeko ye-reflux. Emva kokuphendula, uxinzelelo lokuqala lwe-atmospheric lwachithwa, kwaye i-fraction yangaphambili yasuswa nge-vacuum kwi-kettle ye-distillation, kwaye i-2-chloro-5-methylpyridine ifunyenwe phantsi kweketile. Ukongeza kwi-, kukho iindlela ezahlukeneyo ezahlukeneyo ezisebenzisa i-niacin njengento ekrwada, i-3-methylpyridine njengento ekrwada, i-2-chloro-5-trichloromethyl pyridine njengezinto eziluhlaza. Into eqhelekileyo yezi ndlela kukubunjwa kweringi yepyridine elandelwa kukugqitywa kwe-chloromethylation. Enye indlela ephuhliswe yi-United States Rayleigh Company (i-ReillyIndustriesInc.) ithatha i-cyclopentadiene kunye ne-propanal njengesiqalo sezinto eziluhlaza ukuya ngqo kwi-cyclosynthesize 2-chloro-5-chloromethyl pyridine, kwaye ukucoceka kwemveliso kuphezulu njenge-95%, ngaphandle kwe-isomer 2. -chloro-3-chloromethyl pyridine.
25Kg / umphanda; Ukupakisha ngokweemfuno zomthengi.
Le mveliso kufuneka igcinwe kwisitya esivaliweyo kwaye igcinwe kwindawo epholileyo neyomileyo ngexesha lokugcinwa nokuthutha. Musa ukuxubana nee-oxidants zokuthutha kunye nokugcinwa.
