I-2-methyl-5-nitroimidazole
Ulwazi olusisiseko:
Igama leKhemikhali: 2-methyl-5-nitroimidazole;
Igama lesiNgesi: 2-Methyl-5-nitroimidazole;
Inombolo ye-CAS: 88054-22-2
Ifomula yemolekyuli: C4H5N3O2
Ubunzima bemolekyuli: 127.1
Inombolo ye-EINECS: 618-108-7
Ifomula yolwakhiwo:
Iindidi ezinxulumeneyo: imathiriyeli ekrwada; abaphakathi bamayeza; Imathiriyeli ekrwada yamayeza.
Ubuninzi :1.4± 0.1g /cm3
Indawo yokubilisa :399.5±15.0 °C kwi-760 mmHg
Indawo yokunyibilika: 252-254ºC
Indawo edanyazayo:195.4±20.4 °C
Ubunzima obuchanekileyo :127.038177
PSA:74.50000 LogP:-0.10
Imbonakalo: Ikristale emhlophe
Uxinzelelo lomphunga :0.0±0.9 mmHg ku-25°C
Isalathiso seRefractive: 1.592
Iimeko zokugcina: ivalwe kwindawo epholileyo neyomileyo ye-0-6 ºC
Ukuzinza: ayiyi kubola xa isetyenziswa kwaye igcinwe ngokwemigaqo.
| iinkcukacha | iyunithi | umgangatho |
| Imbonakalo | Njengomgubo omhlophe okanye otyheli | |
| Umxholo | % | ≥99% |
| Ukufuma | % | ≤0.3 |
| Isulphate | % | ≤0.3 |
Isetyenziswa ikakhulu kwi-synthesis ye-metronidazole, i-dimetazole kunye nezinye iziyobisi eziphakathi.
Ifunyenwe nge-nitrate ye-2-methylimidazole. Faka i-asidi ye-sulfuric, i-2-methylimidazole kunye ne-sodium sulfate kwi-reaction pot, i-stir and heat, yongeza i-nitric acid kwi-150-160 ℃, yongeza, landela i-casket reaction ngeyure eli-1. Susa ubushushu kwi-140 ℃ ngezantsi, emva kokufaka amanzi nge-ammonia ukulungelelanisa i-pH kwi-3.5-4, i-crystallization. Uxinzelelo, uhlambe ukungathathi hlangothi, owomileyo, i-2-methyl-5-nitroimidazole.
I-25k isikhwama sephepha se-kraft okanye isikhwama esilukiweyo (i-58 × 110) efakwe isikhwama seplastiki, i-250kg isikhwama sokuthumela ngaphandle (100 × 80); Ngokweemfuno zabathengi;
Ukugcinwa okutywiniweyo, okugcinwe kwindawo epholileyo, emnyama, eyomileyo, ukugcinwa kunye nokuthutha kufuneka kube lula, ukukhusela umonakalo kunye nomswakama, unqatshelwe ngokungqongqo kunye neziyobisi ezixutywe.
Indlela yokuvelisa: Ifunyenwe nge-nitrate ye-2-methylimidazole. Faka i-asidi ye-sulfuric, i-2-methylimidazole kunye ne-sodium sulfate kwi-reaction pot, i-stir and heat, yongeza i-nitric acid kwi-150-160 ℃, yongeza, landela i-casket reaction ngeyure eli-1. Susa ubushushu kwi-140 ℃ ngezantsi, emva kokufaka amanzi nge-ammonia ukulungelelanisa i-pH kwi-3.5-4, i-crystallization. Uxinzelelo, uhlambe ukungathathi hlangothi, owomileyo, i-2-methyl-5-nitroimidazole.
