I-C42h5O9O9O9O9P cytidine, n-Acetyl-5 -U- [i-bis (4-cythyl- bis (1-Methythyl) phosphoramidite] (AIT)

I-C42h5O9O9O9P cytidine, N-Acetyl-5 -U- [i-bis (4-I-1-I-1-I-1-Methythyl) phosphoramidite]

Ulwazi olusisiseko:

Thumela i-imeyile kuthi

Iinkcukacha zemveliso

Iimpawu zeMveliso

Iinkcukacha

Inombolo yeRegistry yeCas

Ngo-199593-09-4-4-4-4-4-4-4

Iipropathi eziphambili	Ixabiso	Imeko
Ubunzima bemolekyuli	801.87	-
pka (ubungqina)	10.18 ± 0.20	Uninzi lwe-acidic temp: 25 ° C

Amanye amagama kunye nezikhangeli

I-Canonical iyancuma

N # CCCOP (OC1C (OC

I-Ismomeric iyancuma

C (oc [c @@ h] 1 [c @@ h] (O) (C) (C) (C) (C) (C3) (C) (C4 = CC = C (oc) c = c4) c5 = cc = cc = c5

Intshi

I-Inchi = 1s / c42h52O9P / C1-28 (3) -42 (31-13-10-9-11-13,32-16) 22-16) 20-16-16) 20-7h2, ( H, 44,45,48,49) / T36-, 38-, 39-, 40- 57?

Isitshixo se-Inchi

Wnwumiploktez-uaqiplrsa-n

1 elinye igama le nto

I-cytidine,N-U-5 '-O- [BIs (4-I-EAPXXYLL) phenylmethyl] -2 -O-Ethyl-, 3 '- [2-cyanothyl Bis (1-Methylethyl) phosphoramidite (9I)

Iipropathi ezikhoyo
Ibhayimu
Ikhemikhali
Lipinski
Ulwakhiwo olunxulumene

Ibhayimu

Ipropathi	Ixabiso	Imeko	Umthombo
Into yebhayiloji	4.77	pl 1; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	50.1	pl 2; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	2190	pH 3; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-21700	pH 4; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-35700	Ph 5; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-37800	ph 6; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	37900	Ph 7; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	37300	pH 8; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-31400	PH 9; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-12300	Ph 10; Temp: 25 ° C	(1) I-ACD

Ikhemikhali

Imeko yexabiso lePropathi

I-Koc 8.29 ph 1; Temp: I-25 ° C (1) ACD

I-Koc 87.1 pl 2; Temp: I-25 ° C (1) ACD

I-Koc 3800 Ph 3; Temp: I-25 ° C (1) ACD

I-Koc 37700 ph 4; Temp: I-25 ° C (1) ACD

I-Koc 62000 Ph 5; Temp: I-25 ° C (1) ACD

I-Koc 65700 Ph 6; Temp: I-25 ° C (1) ACD

I-Koc 65900 Ph 7; Temp: I-25 ° C (1) ACD

I-Koc 64700 ph 8; Temp: I-25 ° C (1) ACD

I-Koc 54500 PH 9; Temp: I-25 ° C (1) ACD

I-Koc 21400 Ph 10; Temp: I-25 ° C (1) ACD

Ngena 2.43 pl 1; Temp: I-25 ° C (1) ACD

I-LOGD 3.45 Ph 2; Temp: I-25 ° C (1) ACD

I-LOGD 5.09 Ph 3; Temp: I-25 ° C (1) ACD

Ipropathi	Ixabiso	Imeko	Umthombo
Ngena	I-6.09	pH 4; Temp: 25 ° C	(1) I-ACD
Ngena	6.30	Ph 5; Temp: 25 ° C	(1) I-ACD
Ngena	6.33	ph 6; Temp: 25 ° C	(1) I-ACD
Ngena	6.33	Ph 7; Temp: 25 ° C	(1) I-ACD
Ngena	6.32	pH 8; Temp: 25 ° C	(1) I-ACD
Ngena	6.25	PH 9; Temp: 25 ° C	(1) I-ACD
Ngena	5.84	Ph 10; Temp: 25 ° C	(1) I-ACD
I-LOGP	6.329 ± 0.771	Temp: 25 ° C	(1) I-ACD
I-Mass Intrinsic Solince	I-1.8 x 10-4 g / l	Temp: 25 ° C	(1) I-ACD
I-Mass Solity	1.4 g / l	pl 1; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-0.14 g / l	pl 2; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	3.1 x 10-3 g / l	pH 3; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	3.2 x 10-4 g / l	pH 4; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	1.9 x 10-4 g / l	Ph 5; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-1.8 x 10-4 g / l	ph 6; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-1.8 x 10-4 g / l	Ph 7; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-1.8 x 10-4 g / l	pH 8; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	2.2 x 10-4 g / l	PH 9; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	5.6 x 10-4 g / l	Ph 10; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-1.8 x 10-4 g / l	AMANZI AMANZI AMANZI PH (7.00; Temp: 25 ° C	(1) I-ACD
I-Molar Intrinsic Solin	2.3 x 10-7 mol / l	Temp: 25 ° C	(1) I-ACD
I-Molar Solity	1.8 x 10-3 mol / l	pl 1; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	I-1.7 x 10-4 mol / l	pl 2; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	3.9 x 10-6 mol / l	pH 3; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	4.0 x 10-7 mol / l	pH 4; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.4 x 10-7 mol / l	Ph 5; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.3 x 10-7 mol / l	ph 6; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.3 x 10-7 mol / l	Ph 7; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.3 x 10-7 mol / l	pH 8; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.8 x 10-7 mol / l	PH 9; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	7.0 x 10-7 mol / l	Ph 10; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.3 x 10-7 mol / l	AMANZI AMANZI AMANZI PH (7.00; Temp: 25 ° C	(1) I-ACD

Ipropathi	Ixabiso	Imeko	Umthombo
Ubunzima bemolekyuli	801.87
pka	10.18 ± 0.20	Uninzi lwe-acidic temp: 25 ° C	(1) I-ACD
pka	3.57 ± 0.20	Uninzi lwe-temp olusisiseko: i-25 ° C	(1) I-ACD

Lipinski

Ipropathi	Ixabiso	Imeko	Umthombo
I-Bonds ejikelezayo	18		(1) I-ACD
I-H Acceptors	14		(1) I-ACD
H abanikeli	1		(1) I-ACD
H umxhasi / i-acceptor sum	15		(1) I-ACD
I-LOGP	6.329 ± 0.771	Temp: 25 ° C	(1) I-ACD
Ubunzima bemolekyuli	801.87