I-C44H53FN7O8 Guanosine, 5 -O- [i-bis (4-I-1-I-bis-bis (1-Methyl Ethyl) phosphoramidite] (AII)

Ulwazi olusisiseko:

Thumela i-imeyile kuthi

Iinkcukacha zemveliso

Iimpawu zeMveliso

Iinkcukacha

Inombolo yeRegistry yeCas

144089-97-4

Iipropathi eziphambili	Ixabiso	Imeko
Ubunzima bemolekyuli	857.91	-
pka (ubungqina)	9.16 ± 0.20	Uninzi lwe-acidic temp: 25 ° C

Amanye amagama kunye nezikhangeli

I-Canonical iyancuma

I-N # CCCOP (OC1C (F) C (F) C (c = cc = c) c) c (c3) c (c) c) c

I-Ismomeric iyancuma

C (oc [c @@ h] 1 [c @ fam h) (C) (C) (C) (C) (C) (C)) c = C4) (c5 = cc = c (OC) c = c5) c6 = cc = cc = c6

Intshi

I-Inchi = 1s / c44h53fn7OP / C1-27 (2) 49-36 (45) 48-16 (5) (5) 6) 35 (59-42) 25-544 (30-13-11-11-11-15-31) 24-25h2,18H3, (H2,48,49,45,50,53,53,53,53,51) / T35-, 31-, 6 / s1

Isitshixo se-Inchi

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1 elinye igama le nto

IGuanosine, 5 '-O- [BIs (4-INDAWO) phenylmethyl] -2 '-Deoxy-2' -Fluoro-N- (I-2-methyl-1-1-I-Opupropyl) -, 3 '- [2-cyanothyl Bis (1-Methyl Ethyl) phosphoramiditer (9I)

Xela kwangaphambili iipropathi

Iipropathi ezikhoyo
Ibhayimu
Ikhemikhali
Lipinski
Ulwakhiwo olunxulumene

Ibhayimu

Ipropathi	Ixabiso	Imeko	Umthombo
Into yebhayiloji	298	pl 1; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-6350	pl 2; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	I-57800	pH 3; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	1.76 X 105	pH 4; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	2.21 x 105	Ph 5; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	2.26 X 105	ph 6; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	2.24 X 105	Ph 7; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	2.03 x 105	pH 8; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	1.04 X 105	PH 9; Temp: 25 ° C	(1) I-ACD
Into yebhayiloji	Ngo-19300	Ph 10; Temp: 25 ° C	(1) I-ACD

Ikhemikhali

Imeko yexabiso lePropathi

I-Koc 312 Ph 1; Temp: I-25 ° C (1) ACD

I-Koc 6630 ph 2; Temp: I-25 ° C (1) ACD

I-Koc 60400 ph 3; Temp: I-25 ° C (1) ACD

I-Koc 1.84 x 105 ph 4; Temp: I-25 ° C (1) ACD

Koc 2.31 x 105 ph 5; Temp: I-25 ° C (1) ACD

I-Koc 2.37 X 105 v 6; Temp: I-25 ° C (1) ACD

I-Koc 2.35 x 105 ph 7; Temp: I-25 ° C (1) ACD

I-Koc 2.12 X 105 v 8; Temp: I-25 ° C (1) ACD

I-Koc 1.08 x 105 ph 9; Temp: I-25 ° C (1) ACD

I-Koc 20200 Ph 10; Temp: I-25 ° C (1) ACD

I-LOGD 4.47 pl 1; Temp: I-25 ° C (1) ACD

I-LOGD 5.80 Ph 2; Temp: I-25 ° C (1) ACD

Ipropathi	Ixabiso	Imeko	Umthombo
Ngena	6.76	pH 3; Temp: 25 ° C	(1) I-ACD
Ngena	7.24	pH 4; Temp: 25 ° C	(1) I-ACD
Ngena	7.34	Ph 5; Temp: 25 ° C	(1) I-ACD
Ngena	7.35	ph 6; Temp: 25 ° C	(1) I-ACD
Ngena	7.35	Ph 7; Temp: 25 ° C	(1) I-ACD
Ngena	7.30	pH 8; Temp: 25 ° C	(1) I-ACD
Ngena	7.01	PH 9; Temp: 25 ° C	(1) I-ACD
Ngena	6.28	Ph 10; Temp: 25 ° C	(1) I-ACD
I-LOGP	7.351 ± 0.713	Temp: 25 ° C	(1) I-ACD
I-Mass Intrinsic Solince	I-3.0 x 10-5 g / l	Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-0.022 g / l	pl 1; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	1.0 x 10-3 g / l	pl 2; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	1.2 x 10-4 g / l	pH 3; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	3.9 x 10-5 g / l	pH 4; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	3.1 x 10-5 g / l	Ph 5; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-3.0 x 10-5 g / l	ph 6; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-3.0 x 10-5 g / l	Ph 7; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	3.3 x 1-5 g / l	pH 8; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	6.5 x 10-5 g / l	PH 9; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	3.5 x 10-4 g / l	Ph 10; Temp: 25 ° C	(1) I-ACD
I-Mass Solity	I-3.0 x 10-5 g / l	AMANZI AMANZI AMANZI PH (7.00; Temp: 25 ° C	(1) I-ACD
I-Molar Intrinsic Solin	3.5 x 10-8 mol / l	Temp: 25 ° C	(1) I-ACD
I-Molar Solity	2.6 x 10-5 mol / l	pl 1; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	1.2 x 10-6 mol / l	pl 2; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	1.4 x 10-7 mol / l	pH 3; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	4.5 x 10-8 mol / l	pH 4; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	I-3.6 x 10-8 mol / l	Ph 5; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	3.5 x 10-8 mol / l	ph 6; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	3.5 x 10-8 mol / l	Ph 7; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	3.9 x 10-8 mol / l	pH 8; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	7.6 x 10-8 mol / l	PH 9; Temp: 25 ° C	(1) I-ACD
I-Molar Solity	4.1 x 10-7 mol / l	Ph 10; Temp: 25 ° C	(1) I-ACD

Ipropathi	Ixabiso	Imeko	Umthombo
I-Molar Solity	3.5 x 10-8 mol / l	AMANZI AMANZI AMANZI PH (7.00; Temp: 25 ° C	(1) I-ACD
Ubunzima bemolekyuli	857.91
pka	9.16 ± 0.20	Uninzi lwe-acidic temp: 25 ° C	(1) I-ACD
pka	3.45 ± 0.70	Uninzi lwe-temp olusisiseko: i-25 ° C	(1) I-ACD

Ulwakhiwo olunxulumene

Ipropathi	Ixabiso	Imo yemeko
Indawo yendawo yokuhlala	I-184 A2	(1) I-ACD

Lipinski

Ipropathi	Ixabiso	Imeko	Umthombo
I-Bonds ejikelezayo	18		(1) I-ACD
I-H Acceptors	15		(1) I-ACD
H abanikeli	2		(1) I-ACD
H umxhasi / i-acceptor sum	17		(1) I-ACD
I-LOGP	7.351 ± 0.713	Temp: 25 ° C	(1) I-ACD
Ubunzima bemolekyuli	857.91