isosorbide nitrate

imveliso

isosorbide nitrate

Ulwazi olusisiseko:

Igama leKhemikhali: isosorbide dinitrate; 1,4:3, 6-didehydration D-sorbitan dinitrate

Inombolo yeCAS: 87-33-2

Ifomula yemolekyuli: C6H8N2O8

Ubunzima bemolekyuli: 236.14

Inombolo ye-EINECS: 201-740-9

Ifomula yolwakhiwo:

图片6

Iindidi ezinxulumeneyo: imathiriyeli ekrwada; abaphakathi bamayeza; Imathiriyeli ekrwada yamayeza.


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ipropati yePhysicochemical

Indawo yokunyibilika: 70 °C (lit.)

Indawo yokubila: 378.59°C (uqikelelo olurhabaxa)

Ubuninzi: 1.7503 (uqikelelo olurhabaxa)

Isalathiso seRefractive: 1.5010 (uqikelelo)

Indawo edanyazayo: 186.6±29.9 ℃

Ukunyibilika: Inyibilika kwichloroform, iacetone, inyibilika kancinane kwi-ethanol, inyibilika kancinane emanzini.

Iipropati: Umgubo omhlophe okanye omhlophe wekristale, ongenavumba.

Uxinzelelo lomphunga: 0.0±0.8 mmHg ku-25℃

Isalathiso sokucaciswa

iinkcukacha iyunithi umgangatho
Imbonakalo   Umgubo omhlophe okanye omhlophe wekristale
Ubunyulu % ≥99%
Ukufuma % ≤0.5

 

Isicelo seMveliso

I-Isosorbide nitrate yi-vasodilator esenzo sayo esiphambili se-pharmacological kukuphumza i-vascular smooth muscle. Isiphumo esipheleleyo kukunciphisa ukusetyenziswa kwe-oksijini yemisipha yentliziyo, ukwandisa ukunikezelwa kwe-oksijini, kunye nokunciphisa i-angina pectoris. Ikliniki ingasetyenziselwa ukunyanga iintlobo ezahlukeneyo ze-coronary heart disease angina pectoris kunye nokukhusela ukuhlaselwa. I-Intravenous drip ingasetyenziselwa unyango lwe-congestive heart failure, iintlobo ezahlukeneyo zoxinzelelo lwegazi kwiimeko ezingxamisekileyo kunye nolawulo lwe-pre-operative hypertension.

Iinkcukacha kunye nokugcinwa

25g/ igubu, igubu lekhadibhodi; Ukugcinwa okutywiniweyo, umoya ophantsi wokungenisa umoya kunye ne-warehouse eyomileyo, i-fireproof, isitoreji esahlukileyo kwi-oxidizer.


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